Title : Novel developments in the use of antimetabolites.

Pub. Date : 2014

PMID : 24940694






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The cytidine-analog fluorocyclopentenylcytosine (RX-3117) is active in gemcitabine-resistant tumors and is activated by uridine-cytidine-kinase, can be incorporated into RNA and DNA and can downregulate DNA-methyltransferase-1. fluorocyclopentenylcytosine DNA methyltransferase 1 Homo sapiens
2 The cytidine-analog fluorocyclopentenylcytosine (RX-3117) is active in gemcitabine-resistant tumors and is activated by uridine-cytidine-kinase, can be incorporated into RNA and DNA and can downregulate DNA-methyltransferase-1. fluorocyclopentenylcytosine DNA methyltransferase 1 Homo sapiens