Title : MIF family members cooperatively inhibit p53 expression and activity.

Pub. Date : 2014

PMID : 24932684






2 Functional Relationships(s)
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1 Finally, increased p53 activation was found to be independent of aberrantly activated AMP-activated protein kinase (AMPK) that occurs in response to MIF/D-DT-deficiency but is dependent on reactive oxygen species (ROS) that mediate aberrant AMPK activation in these cells. Reactive Oxygen Species tumor protein p53 Homo sapiens
2 Finally, increased p53 activation was found to be independent of aberrantly activated AMP-activated protein kinase (AMPK) that occurs in response to MIF/D-DT-deficiency but is dependent on reactive oxygen species (ROS) that mediate aberrant AMPK activation in these cells. Reactive Oxygen Species tumor protein p53 Homo sapiens