Title : CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo.

Pub. Date : 2014 Aug 5

PMID : 24931161






1 Functional Relationships(s)
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1 CLM29 (a pyrazolo[3,4-d]pyrimidine, that inhibits RET, epidermal growth factor receptor, vascular endothelial growth factor receptor, and has an anti-angiogenic activity) has anti-neoplastic activity in papillary dedifferentiated thyroid cancer. pyrazolo(3,4-d)pyrimidine ret proto-oncogene Homo sapiens