Pub. Date : 2014 Jun 14
PMID : 24928142
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Peripheral administration of morphine attenuates postincisional pain by regulating macrophage polarization through COX-2-dependent pathway. | Morphine | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
2 | Conversely, cyclooxygenase (COX)-2, primarily produced from peripheral macrophages in acute inflammation states, was up-regulated in the early phase at morphine-injected sites. | Morphine | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
3 | A morphine-induced shift in macrophage phenotype may be mediated by a COX-2-dependent mechanism. | Morphine | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |