Title : Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells.

Pub. Date : 2014 Jun 13

PMID : 24928086






2 Functional Relationships(s)
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Protein Name
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1 In D2 cells, LPA induced EGFR transactivation, but this was associated with slowing of a very high inherent migration rate in these cells. lysophosphatidic acid epidermal growth factor receptor Homo sapiens
2 CONCLUSION: The results demonstrate LPA-stimulated migration in oral carcinoma cells through LPAR3, mediated further by PKC, which acts either in concert with or independently of EGFR transactivation. lysophosphatidic acid epidermal growth factor receptor Homo sapiens