Title : NADPH oxidase mediates TNF-α-evoked in vitro brain barrier dysfunction: roles of apoptosis and time.

Pub. Date : 2014 Jul

PMID : 24907586






1 Functional Relationships(s)
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1 Suppression of NADPH oxidase by apocynin or diphenyleneiodonium prevented TNF-alpha-evoked morphological changes and apoptosis, attenuated endothelial MMP activity and helped retain usual tight junction protein expression and barrier function. diphenyleneiodonium tumor necrosis factor Homo sapiens