Title : GPER mediates activation of HIF1α/VEGF signaling by estrogens.

Pub. Date : 2014 Aug 1

PMID : 24894716






1 Functional Relationships(s)
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1 We demonstrated that 17beta-estradiol (E2) and the GPER-selective ligand G-1 triggered a GPER/EGFR/ERK/c-fos signaling pathway that leads to increased VEGF via upregulation of HIF1alpha. Estradiol mitogen-activated protein kinase 1 Homo sapiens