Pub. Date : 2014 Jun 3
PMID : 24894398
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | All-trans-retinoic acid also inhibited the TGF-beta-induced phosphorylation of the mitogen-activated protein kinases (MAPKs) extracellular signal-regulated kinase (ERK), p38, and c-Jun NH2-terminal kinase (JNK) as well as that of c-Jun and Smad2/3. | Tretinoin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | CONCLUSIONS: All-trans-retinoic acid inhibited TGF-beta-induced collagen gel contraction mediated by HTFs, most likely by attenuating the formation of actin stress fibers and focal adhesions as well as signaling by MAPKs, c-Jun, and Smads. | Tretinoin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |