Pub. Date : 2014 Jul
PMID : 24887412
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GFR was reduced by 33% of the controls 12 h after GalN/LPS exposure, accompanied with a decreased serum sodium levels, a marked increase in serum TNF-alpha and ET-1 levels as well as significantly upregulated renal type 1 inositol 1,4,5-trisphosphate receptor (IP3R1) expression. | Galactosamine | tumor necrosis factor | Rattus norvegicus |
| 2 | Treatments with either TNF-alpha antibodies or 2-APB also significantly improved the compromised GFR, elevated serum urea nitrogen and creatinine levels, and reversed the decrease in glomerular inulin space and the increase in glomerular calcium content in GalN/LPS-exposed rats. | Galactosamine | tumor necrosis factor | Rattus norvegicus |