Title : High density lipoprotein from patients with valvular heart disease uncouples endothelial nitric oxide synthase.

Pub. Date : 2014 Sep

PMID : 24887036






1 Functional Relationships(s)
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1 Simvastatin therapy partially reduced HDL inflammation index, improved the capacity of HDL to stimulate eNOS and Akt phosphorylation at S1177, eNOS associated with HSP90, NO production, reduced eNOS phosphorylation at T495 and superoxide generation, and improved endothelium-dependent vasodilation. Simvastatin AKT serine/threonine kinase 1 Homo sapiens