Title : Latent transforming growth factor-β1 protects against bleomycin-induced lung injury in mice.

Pub. Date : 2014 Dec

PMID : 24885478






1 Functional Relationships(s)
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1 Compared with littermate wild-type (WT) mice, TGF-beta1(wt) Tg mice had over twofold-higher levels of latent TGF-beta1 in both plasma and lung tissue, and were protected from bleomycin-induced pulmonary inflammation, such as up-regulation of IL-1beta, TNF-alpha, and macrophage chemotactic protein-1, and infiltration of CD3(+) T cells and F4/80(+) macrophages. Bleomycin interleukin 1 beta Mus musculus