Title : Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer.

Pub. Date : 2014 Apr 30

PMID : 24884806






2 Functional Relationships(s)
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1 BACKGROUND: Expression and function of sodium iodide symporter (NIS) is requisite for efficient iodide transport in thyrocytes, and its presence in cancer cells allows the use of radioiodine as a diagnostic and therapeutic tool in thyroid neoplasia. Iodine-131 solute carrier family 5 member 5 Homo sapiens
2 Moreover, stimulation of endogenous NIS expression may permit the radioiodine treatment of extrathyroidal lesions by concentrating this radioisotope. Iodine-131 solute carrier family 5 member 5 Homo sapiens