Title : Valproate pretreatment protects pancreatic β-cells from palmitate-induced ER stress and apoptosis by inhibiting glycogen synthase kinase-3β.

Pub. Date : 2014 May 4

PMID : 24884462






2 Functional Relationships(s)
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1 Recent literature suggests that valproate, a diffusely prescribed drug in the treatment of epilepsy and bipolar disorder, can inhibit glycogen synthase kinase-3beta (GSK-3beta) activity and has cytoprotective effects in neuronal cells and HepG2 cells. Valproic Acid glycogen synthase kinase 3 beta Homo sapiens
2 Recent literature suggests that valproate, a diffusely prescribed drug in the treatment of epilepsy and bipolar disorder, can inhibit glycogen synthase kinase-3beta (GSK-3beta) activity and has cytoprotective effects in neuronal cells and HepG2 cells. Valproic Acid glycogen synthase kinase 3 beta Homo sapiens