Title : Novel synthesis of dihydropyrimidines for α-glucosidase inhibition to treat type 2 diabetes: in vitro biological evaluation and in silico docking.

Pub. Date : 2014 Jun

PMID : 24880489






2 Functional Relationships(s)
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1 A convenient and efficient new method has been established for the synthesis of dihydropyrimidines by inexpensive and non-toxic N-acetyl glycine (NAG) catalysed reaction of aromatic aldehydes with ethyl acetoacetate and urea/thiourea. Aldehydes N-acetyl-alpha-glucosaminidase Homo sapiens
2 A convenient and efficient new method has been established for the synthesis of dihydropyrimidines by inexpensive and non-toxic N-acetyl glycine (NAG) catalysed reaction of aromatic aldehydes with ethyl acetoacetate and urea/thiourea. Aldehydes N-acetyl-alpha-glucosaminidase Homo sapiens