Title : Anti-inflammatory therapies for cardiovascular disease.

Pub. Date : 2014 Jul 14

PMID : 24864079






2 Functional Relationships(s)
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Protein Name
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1 Promising clinical data for "upstream" biomarkers of inflammation such as interleukin-6 (IL-6) as well as "downstream" biomarkers such as C-reactive protein, observations regarding cholesterol crystals as an activator of the IL-1beta generating inflammasome, and recent Mendelian randomization data for the IL-6 receptor support the hypothesis that inflammatory mediators of atherosclerosis may converge on the central IL-1, tumour necrosis factor (TNF-alpha), IL-6 signalling pathway. Cholesterol interleukin 6 Homo sapiens
2 Promising clinical data for "upstream" biomarkers of inflammation such as interleukin-6 (IL-6) as well as "downstream" biomarkers such as C-reactive protein, observations regarding cholesterol crystals as an activator of the IL-1beta generating inflammasome, and recent Mendelian randomization data for the IL-6 receptor support the hypothesis that inflammatory mediators of atherosclerosis may converge on the central IL-1, tumour necrosis factor (TNF-alpha), IL-6 signalling pathway. Cholesterol interleukin 6 Homo sapiens