Title : DMRT1 protects male gonadal cells from retinoid-dependent sexual transdifferentiation.

Pub. Date : 2014 Jun 9

PMID : 24856513






2 Functional Relationships(s)
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1 We find that DMRT1 blocks testicular retinoic acid (RA) signaling from activating genes normally involved in female sex determination and ovarian development and show that inappropriate activation of these genes can drive sexual transdifferentiation. Tretinoin doublesex and mab-3 related transcription factor 1 Homo sapiens
2 We find that DMRT1 blocks testicular retinoic acid (RA) signaling from activating genes normally involved in female sex determination and ovarian development and show that inappropriate activation of these genes can drive sexual transdifferentiation. Tretinoin doublesex and mab-3 related transcription factor 1 Homo sapiens