Pub. Date : 2014 Jul 15
PMID : 24856059
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-alpha. | caryophyllene | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 2 | We demonstrated that trans-caryophyllene, a flavor compound in plant foods and teas, activates peroxisome proliferator-activated receptor (PPAR)-alpha through direct interaction with the ligand-binding domain of PPAR-alpha. | caryophyllene | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 3 | We demonstrated that trans-caryophyllene, a flavor compound in plant foods and teas, activates peroxisome proliferator-activated receptor (PPAR)-alpha through direct interaction with the ligand-binding domain of PPAR-alpha. | caryophyllene | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 4 | In HepG2 cells transfected with small interfering RNA of PPAR-alpha, the effects of trans-caryophyllene on PPAR-alpha responsive gene expressions, intracellular triglyceride, fatty acid uptake and oxidation were disappeared. | caryophyllene | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 5 | In HepG2 cells transfected with small interfering RNA of PPAR-alpha, the effects of trans-caryophyllene on PPAR-alpha responsive gene expressions, intracellular triglyceride, fatty acid uptake and oxidation were disappeared. | caryophyllene | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 6 | These results indicate that the aroma compound, trans-caryophyllene, is PPAR-alpha agonist thus regulates cellular lipid metabolism in PPAR-alpha dependent manners. | caryophyllene | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 7 | These results indicate that the aroma compound, trans-caryophyllene, is PPAR-alpha agonist thus regulates cellular lipid metabolism in PPAR-alpha dependent manners. | caryophyllene | peroxisome proliferator activated receptor alpha | Homo sapiens |