Title : Hirsutenone reduces deterioration of tight junction proteins through EGFR/Akt and ERK1/2 pathway both converging to HO-1 induction.

Pub. Date : 2014 Jul 15

PMID : 24853984






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Hirsutenone prevented the t-BH-induced increase in permeability by inhibiting the reduction in zonula occludens-1 (ZO-1) expression, and rapidly stimulated tyrosine phosphorylation of the epidermal growth factor receptor (EGFR). tert-Butylhydroperoxide tight junction protein 1 Mus musculus
2 Hirsutenone prevented the t-BH-induced increase in permeability by inhibiting the reduction in zonula occludens-1 (ZO-1) expression, and rapidly stimulated tyrosine phosphorylation of the epidermal growth factor receptor (EGFR). tert-Butylhydroperoxide tight junction protein 1 Mus musculus