Pub. Date : 2015 Feb
PMID : 24849496
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Further assays with 200 muM H2O2 induces significant changes in the levels of lactate dehydrogenase (LDH), nitric oxide (NO), reactive oxygen species (ROS) and calcium ion (Ca(2+)) in neuronal cells, but insulin can effectively diminish the oxidative damages. | Hydrogen Peroxide | insulin | Homo sapiens |
| 2 | Moreover, cells treated with insulin increased the H2O2-induced suppression of glutathione levels and exerted an apparent suppressive effect on oxidative products. | Hydrogen Peroxide | insulin | Homo sapiens |
| 3 | The results of Akt, Bcl-2, Bax, IRbeta, IGF-1Rbeta, IRS-1 and IRS-2 showed that insulin treatment had a protective effect on H2O2-induced oxidative stress in RA-differentiated SH-SY5Y neuroblastoma cells. | Hydrogen Peroxide | insulin | Homo sapiens |