Title : Silencing of Dicer1 temporally separates pro- and anti-apoptotic signaling and confers susceptibility to chemotherapy in p53 mutated cells.

Pub. Date : 2014

PMID : 24846461






1 Functional Relationships(s)
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1 We here show that this temporal separation of pro- and anti-apoptotic signaling induced by inhibition of Dicer1 is synergistic and synthetic lethal to low-dose 5-FU chemotherapy in p53-mutated HACAT cells. Fluorouracil tumor protein p53 Homo sapiens