Title : Differences between sites of binding to DNA and strand cleavage for complexes of bleomycin with iron or cobalt.

Pub. Date : 1989 Apr

PMID : 2483675






1 Functional Relationships(s)
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1 The iron-bleomycin (Fe-BLM) complex cleaved the DNA molecules preferentially at dinucleotides GpT and GpC, whereas the light-activated cobalt-bleomycin complex (Co-BLM) showed a preference for cutting at the dinucleotide GpA in addition to cleavage at every GpT dinucleotide. Dinucleoside Phosphates glutamic--pyruvic transaminase Homo sapiens