Pub. Date : 2014 May 15
PMID : 24832603
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Estradiol promotes pentose phosphate pathway addiction and cell survival via reactivation of Akt in mTORC1 hyperactive cells. | Pentosephosphates | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Collectively, these data indicate that estradiol promotes glucose metabolism in mTORC1 hyperactive cells through the pentose phosphate pathway via Akt reactivation and G6PD upregulation, thereby enhancing cell survival under oxidative stress. | Pentosephosphates | thymoma viral proto-oncogene 1 | Mus musculus |