Title : Pharmacoepigenetics of depression: no major influence of MAO-A DNA methylation on treatment response.

Pub. Date : 2015 Jan

PMID : 24809685






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1 However, the presently observed trend towards CpG-specific MAO-A gene hypomethylation-possibly via increased gene expression and consecutively decreased serotonin and/or norepinephrine availability-to potentially drive impaired antidepressant treatment response in female patients might be worthwhile to be followed up in larger pharmacoepigenetic studies. Norepinephrine monoamine oxidase A Homo sapiens