Pub. Date : 2014 Aug
PMID : 24803348
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gold(I) N-heterocyclic carbene complexes with naphthalimide ligands as combined thioredoxin reductase inhibitors and DNA intercalators. | Naphthalimides | peroxiredoxin 5 | Homo sapiens |
| 2 | The complexes were potent DNA intercalators related to their naphthalimide partial structure, inhibited TrxR as a consequence of the incorporation of the gold(I) moiety, and triggered efficient cytotoxic effects in MCF-7 breast and HT-29 colon adenocarcinoma cells. | Naphthalimides | peroxiredoxin 5 | Homo sapiens |