Title : Danhong injection inhibits the development of atherosclerosis in both Apoe⁻/⁻ and Ldlr⁻/⁻ mice.

Pub. Date : 2014 May

PMID : 24803317






2 Functional Relationships(s)
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1 In addition to attenuation of lipopolysaccharide-induced expression of TNF-alpha, IL-1beta, IL-6 in macrophages, and human C-reactive protein in hepatocytes, respectively, at the transcriptional level in vitro, DHI also reduced TNF-alpha protein expression in aortic root of both Apoe-/- and Ldlr-/- mice, suggesting the importance of the anti-inflammatory properties of DHI in the inhibition of lesion development. dehydrosoyasaponin I interleukin 1 beta Homo sapiens
2 In addition to attenuation of lipopolysaccharide-induced expression of TNF-alpha, IL-1beta, IL-6 in macrophages, and human C-reactive protein in hepatocytes, respectively, at the transcriptional level in vitro, DHI also reduced TNF-alpha protein expression in aortic root of both Apoe-/- and Ldlr-/- mice, suggesting the importance of the anti-inflammatory properties of DHI in the inhibition of lesion development. dehydrosoyasaponin I interleukin 1 beta Homo sapiens