Pub. Date : 2014 May
PMID : 24803317
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We observed that DHI inhibited lesions in both Apoe-/- and Ldlr-/- mice. | dehydrosoyasaponin I | apolipoprotein E | Mus musculus |
| 2 | Although DHI reduced HMG-CoA reductase messenger RNA expression in both female Apoe-/- and Ldlr-/- mice, it decreased low-density lipoprotein cholesterol levels only in female Apoe-/- mice. | dehydrosoyasaponin I | apolipoprotein E | Mus musculus |
| 3 | Although DHI reduced HMG-CoA reductase messenger RNA expression in both female Apoe-/- and Ldlr-/- mice, it decreased low-density lipoprotein cholesterol levels only in female Apoe-/- mice. | dehydrosoyasaponin I | apolipoprotein E | Mus musculus |
| 4 | Taken together, our study demonstrates that DHI inhibits atherosclerosis in both Apoe-/- and Ldlr-/- mice with various mechanisms, including anti-inflammation. | dehydrosoyasaponin I | apolipoprotein E | Mus musculus |