Title : Disruption of follicular dendritic cells-follicular lymphoma cross-talk by the pan-PI3K inhibitor BKM120 (Buparlisib).

Pub. Date : 2014 Jul 1

PMID : 24799524






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BKM120 inhibits both constitutive PI3K/AKT pathway and FDC- or CXCL12-induced PI3K/AKT pathway, hampers FDC survival signaling, and reduces cell proliferation of FL cells in vitro and in mouse xenografts. NVP-BKM120 thymoma viral proto-oncogene 1 Mus musculus
2 BKM120 inhibits both constitutive PI3K/AKT pathway and FDC- or CXCL12-induced PI3K/AKT pathway, hampers FDC survival signaling, and reduces cell proliferation of FL cells in vitro and in mouse xenografts. NVP-BKM120 thymoma viral proto-oncogene 1 Mus musculus