Title : Synthesis of N-benzenesulfonamide-1H-pyrazoles bearing arylsulfonyl moiety: novel celecoxib analogs as potent anti-inflammatory agents.

Pub. Date : 2014 Jun 10

PMID : 24794773






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compound 15d appeared selectivity index (COX-2/COX-1) almost the half of celecoxib while 15c is non-selective for COX-2. Celecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens