Title : Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4.

Pub. Date : 2015 Sep

PMID : 24788960






1 Functional Relationships(s)
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1 With SA-beta-Gal staining, we show that Klf4(-/-) MEFs enter senescence earlier than Klf4(+/+) MEFs, and western blot shows accumulation of p21 and p53 with increasing passages. beta-D-galactose Kruppel-like factor 4 (gut) Mus musculus