Title : Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines.

Pub. Date : 2014 Jun

PMID : 24788596






1 Functional Relationships(s)
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1 Furthermore, metformin sensitized ICC cells to certain chemotherapeutic agents, such as sorafenib, 5-fluorouracil and As2O3 by targeting the AMPK/mTOR/HIF-1alpha/MRP1 pathway and ERK. Metformin mitogen-activated protein kinase 1 Homo sapiens