Pub. Date : 2014 Jun
PMID : 24787057
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PRODH maps to chromosome 22q11, a region conferring the highest known genetic risk of schizophrenia, and encodes proline oxidase, which catalyzes proline catabolism. | Proline | proline dehydrogenase 1 | Homo sapiens |
| 2 | This study presents a mechanism by which 25(OH)D insufficiency confers risk of schizophrenia; via proline elevation due to reduced PRODH expression, and a concomitant dysregulation of neurotransmission. | Proline | proline dehydrogenase 1 | Homo sapiens |