Title : Curcumin-primed exosomes mitigate endothelial cell dysfunction during hyperhomocysteinemia.

Pub. Date : 2014 Jun 27

PMID : 24780320






1 Functional Relationships(s)
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1 KEY FINDINGS: Exosomes derived from curcumin-treated (primed) cells (CUR-EXO) alleviated oxidative stress, tight junctions (ZO-1, claudin-5, occludin), adherent junction (VE-cadherin) proteins and EC layer permeability induced during EC damage due to high homocysteine levels (hyperhomocysteinemia). Curcumin occludin Mus musculus