Title : Combined staurosporine and retinoic acid induces differentiation in retinoic acid resistant acute promyelocytic leukemia cell lines.

Pub. Date : 2014 Apr 28

PMID : 24769642






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1 Taken together, we concluded that the combination of ATRA and staurosporine could overcome differentiation block via MEK/ERK signaling pathway in ATRA-resistant APL cell lines. Tretinoin mitogen-activated protein kinase 1 Homo sapiens