Title : Impact of AhR, CYP1A1 and GSTM1 genetic polymorphisms on TP53 R273G mutations in individuals exposed to polycyclic aromatic hydrocarbons.

Pub. Date : 2014

PMID : 24761888






3 Functional Relationships(s)
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1 Impact of AhR, CYP1A1 and GSTM1 genetic polymorphisms on TP53 R273G mutations in individuals exposed to polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons cytochrome P450 family 1 subfamily A member 1 Homo sapiens
2 Our findings indicated that polymorphisms of PAH metabolic genes, such as AhR, CYP1A1, GSTM1 polymorphisms may interact with p53 genetic variants and may contribute to PAH related cancers. Polycyclic Aromatic Hydrocarbons cytochrome P450 family 1 subfamily A member 1 Homo sapiens
3 Our findings indicated that polymorphisms of PAH metabolic genes, such as AhR, CYP1A1, GSTM1 polymorphisms may interact with p53 genetic variants and may contribute to PAH related cancers. Polycyclic Aromatic Hydrocarbons cytochrome P450 family 1 subfamily A member 1 Homo sapiens