Title : PGE2 modulates the transcriptional activity of ERRa in prostate stromal cells.

Pub. Date : 2014 Dec

PMID : 24760659






1 Functional Relationships(s)
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1 Furthermore, PGE2 activates the EP2/EP4-cAMP-PI3K-ERK signaling pathway, which enhanced ERRa transcriptional potentiality by increasing ERRa phosphorylation and nuclear translocation, subsequently promoting the expression of its target genes, such as aromatase. Cyclic AMP mitogen-activated protein kinase 1 Homo sapiens