Title : The elongation of primary cilia via the acetylation of α-tubulin by the treatment with lithium chloride in human fibroblast KD cells.

Pub. Date : 2015 Mar

PMID : 24760594






2 Functional Relationships(s)
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1 We found that LiCl mobilizes the alpha-tubulin N-acetyltransferase 1 (alphaTAT1) in the signaling pathway mediating GSK-3beta and adenylate cyclase III. Lithium Chloride glycogen synthase kinase 3 beta Homo sapiens
2 In conclusion, our results suggested that LiCl treatments activate alphaTAT1 by the inhibition of GSK-3beta and promote the alpha-tubulin acetylation, and then elongate the primary cilia. Lithium Chloride glycogen synthase kinase 3 beta Homo sapiens