Title : ACE2 deficiency increases NADPH-mediated oxidative stress in the kidney.

Pub. Date : 2014

PMID : 24760518






1 Functional Relationships(s)
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1 Exogenous Ang II was degraded less efficiently by kidneys from ACE2KO mice than WT mice, and administration of an AT1R blocker (losartan 30 mg/kg/day) resulted in normalization of NADPH oxidase activity in the ACE2KO. Losartan angiotensin II, type I receptor-associated protein Mus musculus