Title : Prostaglandin E2 accelerates invasion by upregulating Snail in hepatocellular carcinoma cells.

Pub. Date : 2014 Jul

PMID : 24760275






1 Functional Relationships(s)
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1 The phosphorylation levels of p65 were significantly decreased in Huh-7 and Hep3B cells after treatment with the Akt signaling inhibitor LY294002 and EP4R agonist for 24 h. Treatment with the NF-kappaB inhibitor pyrrolidine dithiocarbamate (PDTC) at 10 muM for 24 h blocked EP4R-agonist-induced Snail upregulation in Huh-7 and Hep3B cells. Dithiocarbamate nuclear factor kappa B subunit 1 Homo sapiens