Pub. Date : 2014 Feb
PMID : 24753817
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 12-O-Tetradecanoylphorbol-13-Acetate Induces Keratin 8 Phosphorylation and Reorganization via Expression of Transglutaminase-2. | Tetradecanoylphorbol Acetate | transglutaminase 2 | Homo sapiens |
| 2 | TPA induced phosphorylation and reorganization of K8 and transglutaminase-2 (Tgase-2) expression in a time- and dose-dependent manner in PANC-1 cells. | Tetradecanoylphorbol Acetate | transglutaminase 2 | Homo sapiens |
| 3 | TPA induced phosphorylation and reorganization of K8 and transglutaminase-2 (Tgase-2) expression in a time- and dose-dependent manner in PANC-1 cells. | Tetradecanoylphorbol Acetate | transglutaminase 2 | Homo sapiens |
| 4 | We next investigated, using cystamine (CTM), Tgase inhibitor, and Tgase-2 gene silencing, Tgase-2"s possible involvement in TPA-induced K8 phosphorylation and reorganization. | Tetradecanoylphorbol Acetate | transglutaminase 2 | Homo sapiens |
| 5 | We next investigated, using cystamine (CTM), Tgase inhibitor, and Tgase-2 gene silencing, Tgase-2"s possible involvement in TPA-induced K8 phosphorylation and reorganization. | Tetradecanoylphorbol Acetate | transglutaminase 2 | Homo sapiens |
| 6 | Tgase-2 gene silencing, we additionally discovered, suppressed TPA-induced migration of PANC-1 cells and Tgase-2 overexpression induced migration of PANC-1 cells. | Tetradecanoylphorbol Acetate | transglutaminase 2 | Homo sapiens |
| 7 | Overall, these results suggested that TPA induced K8 phosphorylation and reorganization via Tgase-2 expression in PANC-1 cells. | Tetradecanoylphorbol Acetate | transglutaminase 2 | Homo sapiens |