Title : Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.

Pub. Date : 2014

PMID : 24748377






1 Functional Relationships(s)
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1 Ovarian tumors deficient in Brca1 respond to treatment with cisplatin and olaparib, a PARP inhibitor, whereas Brca1-wild type tumors are non-responsive to treatment, recapitulating the relative sensitivities observed in patients. olaparib collagen type XI alpha 2 chain Homo sapiens