Title : Tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 in overweight/obese women with polycystic ovary syndrome compared with weight-matched controls.

Pub. Date : 2014 Jul

PMID : 24743397






1 Functional Relationships(s)
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1 However, hepatic HSD11B1 conversion of oral cortisone to cortisol was impaired (P<0.05), whereas subcutaneous abdominal adipose tissue HSD11B1 mRNA levels and activity were increased (P<0.05) in women with PCOS when compared with controls. Hydrocortisone hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens