Pub. Date : 2014 Jul
PMID : 24742817
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Increased O2(-) levels promote ERK phosphorylation (approx sixfold compared to control; P < 0.001) and downstream transcriptional increase of several genes: HMOX1 (P < 0.05), involved in the protection of chemical reactive species; MDR1 (P < 0.01), responsible for the efflux of xenobiotics in the cell; and CD83 (P < 0.05), a DC maturation marker. | Superoxides | mitogen-activated protein kinase 1 | Homo sapiens |