Pub. Date : 1989 Aug 1
PMID : 2474054
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Most importantly, IL-3 "primes" basophils to release large amounts of leukotriene C4 after challenge with C5a (mean of 50 gp LTC4 per nanograms cellular histamine), while neither peptide alone is capable of inducing the formation of bioactive lipids. | Leukotrienes | complement C5a receptor 1 | Homo sapiens |
| 2 | IL-3 affects the extent but not the time course of basophil degranulation, and leukotriene release of cells sequentially exposed to IL-3 and C5a occurs very rapidly concomitant with degranulation. | Leukotrienes | complement C5a receptor 1 | Homo sapiens |