CPRiL

5 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	Theca cells were obtained from prepubertal gilts and cultured under serum-free conditions for 48 h. Theca cell androstenedione production under basal and luteinizing hormone (LH)-stimulated conditions was significantly increased by adding insulin (1 microgram/ml) to the culture medium.	Androstenedione	insulin	Homo sapiens
2	Treatment of basal and LH-stimulated cultures with increasing concentrations of insulin (0.001-10 micrograms/ml) caused dose- and time-dependent increments in androstenedione production, but the effect was independent of the dose of LH employed.	Androstenedione	insulin	Homo sapiens
3	The ability of insulin to enhance thecal cell androstenedione production was mimicked by somatomedin C, but not by relaxin.	Androstenedione	insulin	Homo sapiens
4	Insulin treatment also caused dose-dependent increments in forskolin- and prostaglandin E2-stimulated accumulation of extracellular cAMP and androstenedione.	Androstenedione	insulin	Homo sapiens
5	Insulin also increased both the basal and LH-stimulated production of progesterone and its precursor pregnenolone, in addition to the increases in androstenedione.	Androstenedione	insulin	Homo sapiens