Pub. Date : 2014
PMID : 24736568
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | E2-dependent activation of GPER-1 lowers testosterone production in isolated rats LCs and in human testis, with statistically and clinically significant drops in testosterone production by 20-30% as compared to estradiol-naive LC. | Testosterone | G protein-coupled estrogen receptor 1 | Rattus norvegicus |
2 | E2-dependent activation of GPER-1 lowers testosterone production in isolated rats LCs and in human testis, with statistically and clinically significant drops in testosterone production by 20-30% as compared to estradiol-naive LC. | Testosterone | G protein-coupled estrogen receptor 1 | Rattus norvegicus |
3 | CONCLUSIONS: Our results indicate that activation of GPER-1 lowers testosterone levels in the rat and human testis. | Testosterone | G protein-coupled estrogen receptor 1 | Rattus norvegicus |