Title : The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy.

Pub. Date : 2014 Jun 15

PMID : 24735610






1 Functional Relationships(s)
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1 Recently, our group has shown that the rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a selective GR ligand that behaves as an agonist in transrepression assays and as an antagonist in transactivation ones. 21oh nuclear receptor subfamily 3, group C, member 1 Mus musculus