Pub. Date : 2014 Jun
PMID : 24729449
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Natural taxane paclitaxel from Taxus brevifolia activated the Raf-1/extracellular signal-regulated kinase (ERK) pathway, leading to an activation of ribosomal S6 kinases (RSK)/YB-1 signaling. | taxane | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | In addition, ERK or RSK was activated in taxane-resistant prostate cancer cells, resulting in YB-1 activation. | taxane | mitogen-activated protein kinase 1 | Homo sapiens |