Title : The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes.

Pub. Date : 1989 Jul 15

PMID : 2472451






1 Functional Relationships(s)
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1 FK506, a neutral macrolide with immunosuppressive properties, was shown to selectively and rapidly inhibit the accumulation of IL-2 mRNA, as well as the mRNAs of other early (E) phase T cell activation genes such as IL-3, IL-4, GM-CSF, TNF alpha, IFN-gamma, and c-myc in activated human peripheral blood T cells. Tacrolimus colony stimulating factor 2 Homo sapiens