Title : Poly(ethylene glycol)-mediated conformational alteration of α-chymotrypsin prevents inactivation of insulin by stabilizing active intermediates.

Pub. Date : 2014 Oct 6

PMID : 24720816






2 Functional Relationships(s)
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1 Poly(ethylene glycol)-mediated conformational alteration of alpha-chymotrypsin prevents inactivation of insulin by stabilizing active intermediates. Polyethylene Glycols insulin Homo sapiens
2 The analysis on the conformation of alpha-CT and the local environment of the enzyme"s active site unraveled that PEG 400 altered the conformation of alpha-CT to prevent the inactivation of insulin via stabilization of active intermediates. Polyethylene Glycols insulin Homo sapiens