Title : Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells.

Pub. Date : 2014 May 13

PMID : 24714748






2 Functional Relationships(s)
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1 We previously demonstrated that Nox4, a Nox family NADPH oxidase, is a TGF-beta/SMAD3-inducible source of reactive oxygen species (ROS) affecting cell migration and fibronectin expression, an EMT marker, in normal and metastatic breast epithelial cells. Reactive Oxygen Species SMAD family member 3 Homo sapiens
2 We previously demonstrated that Nox4, a Nox family NADPH oxidase, is a TGF-beta/SMAD3-inducible source of reactive oxygen species (ROS) affecting cell migration and fibronectin expression, an EMT marker, in normal and metastatic breast epithelial cells. Reactive Oxygen Species SMAD family member 3 Homo sapiens